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Apple Leaves Extract Phloretin for Whitening Agents Lighten Spot 60-82-2

  • Price:

    Negotiable

  • minimum:

  • Total supply:

  • Delivery term:

    The date of payment from buyers deliver within days

  • seat:

    Shaanxi

  • Validity to:

    Long-term effective

  • Last update:

    2018-02-28 20:00

  • Browse the number:

    232

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Company Profile

Shaanxi Huatai Bio-fine Chemical Co.,Ltd

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Contact：somy396(Mr.)  

Email：

Telephone：

Phone：

Area：Shaanxi

Address：Branch Office : Room1513,Jingye Business Building, Wenyi Rd, Xi'an City, Shaanxi , China.

Website：http://www.natural-ingredient.com/ http://somy396.qiaochenglan.com/

Product Details

Apple Leaves Extract Phloretin for Whitening Agents Lighten Spot


Product introduction

Phloretin is a dihydrochalcone compound, is a new natural skin whitening agent, mainly distributed in apples and other juicy fruit peel and root bark. Phloretin has a weak estrogen activity.


Product parameter

 Phloretin

Trade Name: Shaanxi Huatai Bio-fine Chemical Co., Ltd.

Common Name: Phloretin

Chemical Name : 2',4',6'-TRIHYDROXY-3-(4-HYDROXYPHENYL)PROPIOPHENONE

CAS No.: 60-82-2

EINECS No.: 200-488-7

Molecular Formula: C15H14O5

Molecular Structure:                

Characteristics: White powder

Solubility: Dissolved in ethanol, 1,3-butanediol. Do not dissolved in water

Specification: Cosmetic grade

Category: Skin Care

Features: The Studies have shown that phloretin can inhibiting melanocytes, inhibiting tyrosinase activity, and has effects on various skin pigmentation. Phloretin also has Anti-inflammatory and immunosuppressive effects. Research showed that cause the phloretin, NO release volume of macrophage was significantly decreased under the stimulation of lipopolysaccharide (LPS) and IFN-γ.

Typical Dosage: 3‰-5‰

Packing: 1kg aluminum foil bag

Transport: Non-hazardous cargo(IMO/IATA)

Remarks: Safety and efficacy report available upon request.


Product feature application

Anti-inflammatory and immunosuppressive effects. Research showed that cause the phloretin, NO release volume of macrophage was significantly decreased under the stimulation of lipopolysaccharide (LPS) and IFN-γ. Phloretin has a potential anti-inflammatory effect. In immunosuppression, studies have shown that phloretin has a significant inhibitory effect on mouse T lymphocyte activation.

Phloretin induced cytotoxicity on lymphocytes N=6, *±S.control

Group

Dose/μmol·L-1

A

Survival rate/%

Negative


Control

0.140±0.002

/

Positive


Control

0.365±0.007

100

Phloretin

40

0.332±0.013

88.87

60

0.316±0.021

81.48

80

0.297±0.015

72.68

Figure :Proliferation of lymphocytes analyzed by CFSE-labelling (n = 4, x ± s).


Product qualification

Deliver, shipping and serving

Applications: Widely used in cosmetic product as cream, paste, water solution and emulsion.


1. 1kg with double plastic container inside/Aluminum foil bag outside.
2. 25kg with double plastic container inside/Fiber drum outside.
3. The final decision will be made by your company.

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